\u00b7 Tobias Bock, Eric W. Buss, Olivia M. Lofaro, F\u00e9lix Leroy<\/strong>, Bina Santoro, Steven A. Siegelbaum. \u00a0The HCN1 hyperpolarization-activated cyclic nucleotide-gated channel enhances evoked GABA release from parvalbumin positive interneurons.<\/a> BioRxiv<\/em> 2022.11.11.516205; doi: 10.1101\/2022.11.11.516205<\/p>\n\n\n\n \u00b7 Arun Asok, F\u00e9lix Leroy<\/strong>, Cameron Parro, Christopher A. de Solis, Lenzie Ford, Michelle N. Fitzpatrick, Abigail Kalmbach, Rachael Neve, Joseph B Rayman, Eric R. Kandel. A multisensory circuit for gating intense aversive experiences.<\/a> BioRxiv<\/em> <\/strong>2021.05.01.441648; doi: 10.1101\/2021.05.01.441648<\/p>\n\n\n\n \u00b7 Noelia Sofia de Le\u00f3n Reyes, Paula Sierra D\u00edaz, Ramon Nogueira, Antonia Ruiz-Pino, Yuki Nomura, Christopher de Solis, Jay Schulkin, Arun Asok, F\u00e9lix Leroy<\/strong>. Corticotropin-releasing hormone signaling from prefrontal cortex to lateral septum suppresses interaction with familiar mice. Cell <\/em>2023. doi:10.1016\/j.cell.2023.08.010<\/p>\n\n\n\n \u00b7 Merseburg A, Kasemir J, Buss EW, Leroy F<\/strong>, Bock T, Porro A, Barnett A, Tr\u00f6der SE, Engeland B, Stockebrand M. Moroni A, Siegelbaum SA, Isbrandt D, Santoro B. Seizures, behavioral deficits and adverse drug responses in two new genetic mouse models of HCN1 epileptic encephalopathy. <\/a> eLife<\/em> (2022) 11<\/strong>:e70826. https:\/\/doi.org\/10.7554\/eLife.70826<\/p>\n\n\n\n \u00b7 Besnard A, Leroy F<\/strong>. Top-down regulation of motivated behaviors via lateral septum sub-circuits. <\/a>Perpective article in Molecular Psychiatry<\/em> 2022. doi:10.1038\/s41380-022-01599-3. PMID: 35581296<\/p>\n\n\n\n \u00b7 Lopez-Rojas J, de Solis CA, Leroy F<\/strong>, Kandel ER, Siegelbaum SA. A direct lateral entorhinal cortex to hippocampal CA2 circuit conveys social information required for social memory<\/a>. Neuron<\/em> 2022 May 4;110(9):1559-1572.e4. PMID: 35180391<\/p>\n\n\n\n \u00b7 Leroy F, <\/strong>de Solis CA, Boyle LM, Bock Tobias, Lofaro OM, Buss EW, Asok A, Kandel ER, Siegelbaum SA. Enkephalin release from VIP interneurons in the hippocampal CA2\/3a region mediates heterosynaptic plasticity and social memory.<\/a> Molecular Psychiatry<\/em> 2021, doi: 10.1038\/s41380-021-01124-y. PMID: 33990774<\/p>\n\n\n\n \u00b7 Oliva A, Fern\u00e1ndez-Ruiz A, Leroy F<\/strong>, Siegelbaum SA. Hippocampal CA2 sharp-wave ripples reactivate and promote social memory<\/a>. Nature<\/em> 2020 Nov;587(7833):264-269. PMID: 32968277<\/p>\n\n\n\n \u00b7 Asok A, Leroy F<\/strong>, Rayman J and Kandel ER. Molecular Mechanisms of the Memory Trace<\/a><\/em>. Trends in Neuroscience<\/em>. 2019 Jan;42(1):14-22. doi: 10.1016\/j.tins.2018.10.005. PMID:30391015<\/p>\n\n\n\n \u00b7 Leroy F<\/strong>, Park J, Asok A, Brann DH, Meira T, Boyle LM, Buss EW, Kandel ER and Siegelbaum SA. A circuit from hippocampal CA2 to lateral septum disinhibits social aggression<\/a>. Nature<\/em>. 2018 Dec 5; 564(7735):213-218. PMID: 30518859.<\/p>\n\n\n\n \u00b7 Meira T, Leroy F<\/strong>, Buss EW, Park J and Siegelbaum SA. A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics<\/a>. Nature Communication<\/em>. 2018 Oct 9; 9(1):4163. PMID: 30301899<\/p>\n\n\n\n \u00b7 Elgueta C, Leroy F<\/strong>, Vielma AH, Schmachtenberg O, Palacios AG. Electrical coupling between A17 cells enhances reciprocal inhibitory feedback to rod bipolar cells<\/a>. Science Report<\/em>. 2018 Feb 15; 8(1):3123. PMID: 29449585.<\/p>\n\n\n\n \u00b7 Clark A, Leroy F<\/strong>, Martyniuk K, Feng W, McManus E, Bailey M, Javitch J, Balsam P and Kellendonk C. Dopamine D2 receptors in the paraventricular thalamus attenuate cocaine locomotor sensitization<\/a>. eNeuro<\/em>. 2017 Oct 17; 24; 4(5). PMID: 29071300.<\/p>\n\n\n\n \u00b7 Leroy F<\/strong>, Brann DH, Meira T and Siegelbaum SA. Input-timing dependent plasticity in the hippocampal CA2 region and its potential role in social memor<\/a>y. Neuron<\/em>. 2017 Aug 30; 95(5):1089-1102.e5. PMID: 28823730.<\/p>\n\n\n\n \u00b7 Leroy F<\/strong>, Lamotte d’Incamps B. The Preparation of Oblique Spinal Cord Slices for Ventral Root Stimulation.<\/a> Journal of Visual Experiments<\/em>. 2016 Oct 13; (116). PMID:27768090.<\/p>\n\n\n\n \u00b7 Leroy F<\/strong>, Lamotte d\u2019Incamps B and Zytnicki D. Potassium currents dynamically set the recruitment and firing properties of F-type motoneurons in neonatal mice.<\/a> Journal of Neurophysiology<\/em>. 2015 Sep; 114(3):1963-73. PMID: 26269551.<\/p>\n\n\n\n \u00b7 Leroy F<\/strong> and Zytnicki D. I<\/a><\/em>s hyperexcitability really guilty in amyotrophic lateral sclerosis? <\/a>Neural Regeneration Research<\/em>. 2015 Sep; 10(9):1413-5. PMID: 26604899.<\/p>\n\n\n\n \u00b7 Leroy F<\/strong>, Lamotte d\u2019Incamps B, Imhoff-Manuel R and Zytnicki D. Early intrinsic hyperexcitability does not contribute to motoneuron degeneration in amyotrophic lateral sclerosis<\/a>. eLife 2014 Oct 14; (3). PMID: 25313866.<\/p>\n\n\n\n \u00b7 Branchu J, Biondi O, Chali F, Collin T, Leroy F<\/strong>, Mamchaoui K, Makoukji J, Pariset C, Lopes P, Massaad C, Chanoine C, Charbonnier F. Shift from extracellular signal-regulated kinase to AKT\/cAMP response element-binding protein pathway increases survival-motor-neuron expression in spinal-muscular-atrophy-like mice and patient cells.<\/a> J. Neurosci. 2013 Mar 6; 33(10):4280-94. PMID:23467345.<\/p>\n\n\n\n \u00b7 Bouthour W*, Leroy F<\/strong>*, Emmanuelli C, Carnaud M, Dahan M, Poncer J.C and L\u00e9vi S. A human mutation in Gabrg2 associated with generalized epilepsy alters the membrane dynamics of GABAA receptors.<\/a> Cerebral Cortex<\/em>. 2012 Jul; 22(7):1542-53. PMID: 21908847 (*co-first authors).<\/p>\n\n\n\n \u00b7 Nishijima T, Piriz J, Duflot S, Fernandez A.M, Gaitan G, Gomez-Pinedo U, Garcia Verdugo J.M, Leroy F<\/strong>, Soya H, Nu\u00f1ez A and Torres-Aleman I. Neuronal Activity Drives Localized Blood-Brain-Barrier Transport of Serum Insulin-like Growth Factor-I into the CNS.<\/a> Neuron 2010 Sep 9; 67(5):834-46 PMID: 20826314.<\/p>\n\n\n\n \u00b7 Manuel M, Iglesias C, Donnet M, Leroy F<\/strong>, Heckman CJ, Zytnicki D. Fast kinetics, high-frequency oscillations, and subprimary firing range in adult mouse spinal motoneurons.<\/a> Journal of Neuroscience. 2009 Sep 9; 29(36):11246-56. PMID: 19741131.<\/p>\n\n\n\n <\/p>\n","protected":false},"excerpt":{"rendered":" Preprints \u00b7 Tobias Bock, Eric W. Buss, Olivia M. Lofaro, F\u00e9lix Leroy, Bina Santoro, Steven A. Siegelbaum. \u00a0The HCN1 hyperpolarization-activated cyclic nucleotide-gated channel enhances evoked GABA release from parvalbumin positive interneurons. BioRxiv 2022.11.11.516205; doi: 10.1101\/2022.11.11.516205 \u00b7 Arun Asok, F\u00e9lix Leroy, Cameron Parro, Christopher A. de Solis, Lenzie Ford, Michelle N. Fitzpatrick, Abigail Kalmbach, Rachael Neve, … <\/p>\nPeer-reviewed publications<\/h2>\n\n\n\n
2023<\/h2>\n\n\n\n
2022<\/h2>\n\n\n\n
2021<\/h2>\n\n\n\n
2020<\/h2>\n\n\n\n
2019<\/h3>\n\n\n\n
2018<\/h3>\n\n\n\n
2017<\/h3>\n\n\n\n
2016<\/h3>\n\n\n\n
2015<\/h3>\n\n\n\n
2014<\/h3>\n\n\n\n
2013<\/h3>\n\n\n\n
2012<\/h3>\n\n\n\n
2010<\/h3>\n\n\n\n
2009<\/h3>\n\n\n\n